Anti-CD66a + CD66c + CD66d + CD66e antibody [CLB-gran/10, IH4Fc] (ab51670)

Overview

  • Product nameAnti-CD66a + CD66c + CD66d + CD66e antibody [CLB-gran/10, IH4Fc]
    See all CD66a + CD66c + CD66d + CD66e primary antibodies
  • Description
    Mouse monoclonal [CLB-gran/10, IH4Fc] to CD66a + CD66c + CD66d + CD66e
  • SpecificityThe monoclonal antibody is directed against the CD66acde antigen. The monoclonal antibody reacts with 100% of mature human peripheral granulocytes. It reacts weak with malignant cells of patients with B cell derived Chronic Lymphoid Leukaemia (CLL). The monoclonal antibody does not react with normal human peripheral B cells, T cells, monocytes and platelets. In immunohistology the monoclonal antibody reacts with some tissue macrophages and CEA, the Carcino Embryonic Antigen, expressed on colon carcinoma and other carcinomas.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human granulocytes

Properties

Applications

Our Abpromise guarantee covers the use of ab51670 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use at an assay dependent dilution.
    Study of mature granulocytes in peripheral blood.
    Indirect immunofluorescence staining with analysis by flow cytometry or
    fluorescence microscopy.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
    • Tissue specificityFound in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
    • Sequence similaritiesBelongs to the immunoglobulin superfamily. CEA family.
      Contains 7 Ig-like (immunoglobulin-like) domains.
    • Post-translational
      modifications
      Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Antigen CD66 antibody
      • Biliary glycoprotein antibody
      • Carcinoembryonic antigen antibody
      • Carcinoembryonic antigen related cell adhesion molecule 1 antibody
      • Carcinoembryonic antigen related cell adhesion molecule 3 antibody
      • Carcinoembryonic antigen related cell adhesion molecule 5 antibody
      • Carcinoembryonic antigen related cell adhesion molecule 6 antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
      • CD66a antigen antibody
      • CD66d antibody
      • CD66e antibody
      • CD66e antigen antibody
      • CEA antibody
      • CEACAM1 antibody
      • CEACAM3 antibody
      • Ceacam5 antibody
      • CEACAM6 antibody
      • CEAM5_HUMAN antibody
      • Meconium antigen 100 antibody
      see all

    References for Anti-CD66a + CD66c + CD66d + CD66e antibody [CLB-gran/10, IH4Fc] (ab51670)

    ab51670 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab51670.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"