Overview

  • Product name
    Anti-CD66b antibody [GM-2H6]
    See all CD66b primary antibodies
  • Description
    Mouse monoclonal [GM-2H6] to CD66b
  • Specificity
    This antibody exclusively recognizes CD66b (CEACAM8).
  • Tested applications
    Suitable for: Flow Cyt, ELISA, Competitive ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The complete extracellular region of human CD66b (CEACAM8) cDNA.

  • Positive control
    • FC: BOSC23 cells.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    The antibody was purified from cell culture supernatants.
  • Clonality
    Monoclonal
  • Clone number
    GM-2H6
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab48589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
ELISA
Competitive ELISA
  • Application notes
    cELISA: Use at an assay dependent dilution.
    ELISA: Use at an assay dependent dilution.
    Flow Cyt: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Tissue specificity
      Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
    • Sequence similarities
      Belongs to the immunoglobulin superfamily. CEA family.
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Carcinoembryonic antigen CGM6 antibody
      • Carcinoembryonic antigen gene family member 6 antibody
      • Carcinoembryonic antigen related cell adhesion molecule 8 antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 8 antibody
      • CD 66b antibody
      • CD 67 antibody
      • CD66b antibody
      • CD66b antigen antibody
      • CD67 antibody
      • CD67 antigen antibody
      • CEACAM 8 antibody
      • CEACAM8 antibody
      • CEAM8_HUMAN antibody
      • CGM 6 antibody
      • CGM6 antibody
      • NCA 95 antibody
      • NCA95 antibody
      • Non-specific cross-reacting antigen NCA-95 antibody
      • Nonspecific cross reacting antigen NCA 95 antibody
      • Nonspecific cross reacting antigen NCA95 antibody
      see all

    Images

    • Ab48589, staining CD66b (CEACAM8) by Flow Cytometry.
      BOSC23 cells were transiently transfected with expression vectors containing either the cDNA of CEACAM1, CEACAM3-8 or PSG. The latter was expressed as a membrane bound fusion protein. Expression of the constructs was tested with monoclonal antibodies known to recognize the corresponding proteins (CEACAM1, 3, 4, 5 and 6: D14HD11; CEACAM7: BAC2; CEACAM8: Tet2; PSG: BAP3; green curves). An irrelevant monoclonal antibody served as a negative control (black curves). For specificity testing, ab48589 was tested on all CEACAM transfectants. A positive signal was obtained only with CEACAM8 (CD66b) transfected cells (red curve).

    References

    This product has been referenced in:

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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