Overview

  • Product name
    Anti-CD69 antibody [H1.2F3] (Biotin)
    See all CD69 primary antibodies
  • Description
    Armenian Hamster monoclonal [H1.2F3] to CD69 (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: Flow Cyt, IP, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Y245 dendritic epidermal T cell line (Mouse)

  • General notes


    ab25008 augments PMA-induced T-cell proliferation and induces redirected lysis of Fc receptor-bearing target cells by NK cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab25008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 1µg for 106 cells.
IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Acetone fixed tissues.

Target

  • Function
    Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
  • Tissue specificity
    Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.
  • Sequence similarities
    Contains 1 C-type lectin domain.
  • Developmental stage
    Earliest inducible cell surface glycoprotein acquired during lymphoid activation.
  • Post-translational
    modifications
    Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activation inducer molecule (AIM/CD69) antibody
    • Activation inducer molecule antibody
    • AIM antibody
    • BL-AC/P26 antibody
    • BLAC/P26 antibody
    • C-type lectin domain family 2 member C antibody
    • CD69 antibody
    • CD69 antigen (p60, early T-cell activation antigen) antibody
    • CD69 antigen antibody
    • CD69 molecule antibody
    • CD69_HUMAN antibody
    • CLEC2C antibody
    • EA1 antibody
    • Early activation antigen CD69 antibody
    • Early lymphocyte activation antigen antibody
    • Early T cell activation antigen p60 antibody
    • Early T-cell activation antigen p60 antibody
    • GP32/28 antibody
    • Leu23 antibody
    • Leukocyte surface antigen Leu-23 antibody
    • MLR-3 antibody
    • MLR3 antibody
    • VEA antibody
    • Very Early Activation Antigen antibody
    see all

References

This product has been referenced in:
  • Yokoyama WM  et al. Very early (VEA) and very late (VLA) activation antigens have distinct functions in T lymphocyte activation. Immunol Rev 109:153-76 (1989). Read more (PubMed: 2670747) »
  • Yokoyama WM  et al. Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J Immunol 141:369-76 (1988). Read more (PubMed: 2838547) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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