Anti-CD8 antibody, prediluted (ab27089)

Overview

  • Product nameAnti-CD8 antibody, prediluted
    See all CD8 primary antibodies
  • Description
    Rabbit polyclonal to CD8, prediluted
  • Specificityab27089 binds the alpha chain of human CD8.
  • Tested applicationsIHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide comprising the 13 C-terminal amino acids of the cytoplasmic domain of alpha chain of human CD8 molecule.

  • Positive control
    • Tonsil

Properties

Applications

Our Abpromise guarantee covers the use of ab27089 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Use neat for 10 minutes at room temperature.. Antigen retrieval is not essential but boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 minutes may optimise staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionIdentifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
    • Involvement in diseaseDefects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
    • Sequence similaritiesContains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Post-translational
      modifications
      All of the five most C-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.
    • Cellular localizationSecreted and Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD 8 antibody
      • CD 8A antibody
      • CD 8B antibody
      • CD8 antibody
      • CD8 antigen alpha polypeptide antibody
      • CD8 antigen, alpha polypeptide (p32) antibody
      • CD8A antibody
      • CD8a antigen antibody
      • CD8a molecule antibody
      • CD8A_HUMAN antibody
      • CD8B antibody
      • CD8b antigen antibody
      • CD8b antigen isoform 2 antibody
      • CD8b molecule antibody
      • CD8B protein antibody
      • CD8B1 antibody
      • Leu2 antibody
      • Leu2 T lymphocyte antigen antibody
      • Ly3 antibody
      • LYT3 antibody
      • MAL antibody
      • MGC119115 antibody
      • OKT8 T Cell antigen antibody
      • p32 antibody
      • T cell antigen Leu2 antibody
      • T cell co receptor antibody
      • T cell surface glycoprotein CD8 alpha chain antibody
      • T cell surface glycoprotein CD8 beta chain antibody
      • T lymphocyte differentiation antigen T8/Leu 2 antibody
      • T-cell surface glycoprotein CD8 alpha chain antibody
      • T-lymphocyte differentiation antigen T8/Leu-2 antibody
      • T8 T cell antigen antibody
      see all

    Anti-CD8 antibody, prediluted images

    • Human tonsil stained with ab27089.

    References for Anti-CD8 antibody, prediluted (ab27089)

    ab27089 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. 1) Ab27089 is supplier as a pre diluted product and Ab4055 is not. 2) We do not have specific feedback in relation to certain secondary Abs functioning in conjunction with our antibodies; however a list of compatible s...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"