Overview

  • Product nameAnti-CD89 antibody [MIP7c]
    See all CD89 primary antibodies
  • Description
    Mouse monoclonal [MIP7c] to CD89
  • Specificityab53357 recognises the EC1 domain of the CD89 extracellular region.
  • Tested applicationsSuitable for: Flow Cyt, Inhibition Assaymore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Soluble CD89

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone numberMIP7c
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab53357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
Inhibition Assay
  • Application notesFlow Cyt: Use 1µg/100µl as primary antibody.
    Inhib: Use 4µg for 105 cells.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionBinds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
    • Tissue specificityIsoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
    • Sequence similaritiesContains 2 Ig-like C2-type (immunoglobulin-like) domains.
    • Cellular localizationSecreted and Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD89 antibody
      • Fc alpha receptor antibody
      • Fc fragment of IgA, receptor for antibody
      • FCAR antibody
      • FCAR_HUMAN antibody
      • IgA Fc receptor antibody
      • Immunoglobulin alpha Fc receptor antibody
      see all

    Anti-CD89 antibody [MIP7c] images

    • Neutrophil phagocytosis of IgA immune complexes in presence or absence (control) of ab53357.

    References for Anti-CD89 antibody [MIP7c] (ab53357)

    ab53357 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab53357.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"