Overview

  • Product name
    Anti-CD89 antibody [MIP7c]
    See all CD89 primary antibodies
  • Description
    Mouse monoclonal [MIP7c] to CD89
  • Specificity
    ab53357 recognises the EC1 domain of the CD89 extracellular region.
  • Tested applications
    Suitable for: Flow Cyt, Inhibition Assaymore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Soluble CD89

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    MIP7c
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab53357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
Inhibition Assay
  • Application notes
    Flow Cyt: Use 1µg/100µl as primary antibody.
    Inhib: Use 4µg for 105 cells.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
    • Tissue specificity
      Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
    • Sequence similarities
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    • Cellular localization
      Secreted and Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD89 antibody
      • Fc alpha receptor antibody
      • Fc fragment of IgA, receptor for antibody
      • FCAR antibody
      • FCAR_HUMAN antibody
      • IgA Fc receptor antibody
      • Immunoglobulin alpha Fc receptor antibody
      see all

    Images

    • Neutrophil phagocytosis of IgA immune complexes in presence or absence (control) of ab53357.

    References

    ab53357 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab53357.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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