Biotin Anti-CD90 / Thy1 antibody [G7] (ab25285)
Key features and details
- Biotin Rat monoclonal [G7] to CD90 / Thy1
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG2c
Overview
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Product name
Biotin Anti-CD90 / Thy1 antibody [G7]
See all CD90 / Thy1 primary antibodies -
Description
Biotin Rat monoclonal [G7] to CD90 / Thy1 -
Host species
Rat -
Conjugation
Biotin -
Specificity
ab25285 recognises Thy-1.1 and Thy-1.2 alloantigens. -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to CD90/ Thy1. Mouse T cell hybridoma C6/G8
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Epitope
Thy-1 epitope region A. -
General notes
ab25285 has been reported to promote apoptosis of thymocytes and CTL clones, and to mediate adhesion of thymocytes to thymic stroma.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Affinity purified -
Primary antibody notes
ab25285 has been reported to promote apoptosis of thymocytes and CTL clones, and to mediate adhesion of thymocytes to thymic stroma. -
Clonality
Monoclonal -
Clone number
G7 -
Isotype
IgG2c -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab25285 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
Use 1µg for 106 cells.
ab18543 - Rat monoclonal IgG2c, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use 1µg for 106 cells. ab18543 - Rat monoclonal IgG2c, is suitable for use as an isotype control with this antibody. |
Target
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Function
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. -
Sequence similarities
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 21838 Mouse
- SwissProt: P01831 Mouse
- Unigene: 3951 Mouse
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Alternative names
- CD7 antibody
- CD90 antibody
- CD90 antigen antibody
see all
Images
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Flow cytometry analysis of BALB/c mouse splenocytes stained with Rat Anti-Mouse CD90 ab25285 (0.3 µg/106cells) and Rat Anti-Mouse CD3 epsilon-PE ab136222 followed by Streptavidin-FITC.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab25285 has been referenced in 2 publications.
- Lakins MA et al. Cancer-associated fibroblasts induce antigen-specific deletion of CD8+T Cells to protect tumour cells. Nat Commun 9:948 (2018). PubMed: 29507342
- Gunter KC et al. T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4. J Exp Med 159:716-30 (1984). PubMed: 6142077