Anti-CD90 / Thy1 antibody [G7] (PE/Cy5®) (ab25272)

Overview

  • Product nameAnti-CD90 / Thy1 antibody [G7] (PE/Cy5®)
    See all CD90 / Thy1 primary antibodies
  • Description
    Rat monoclonal [G7] to CD90 / Thy1 (PE/Cy5®)
  • ConjugationPE/Cy5®. Ex: 496nm, Em: 670nm
  • Specificityab25272 is specific for Thy-1.1 and Thy-1.2 alloantigens (Thy-1 epitope region A).
  • Tested applicationsSuitable for: Celluar Activation, Functional Studies, Flow Cyt, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notesThis product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.


    ab25272 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. ab25272 has also been reported to promote apoptosis of thymocytes and CTL clones, and to mediate adhesion of thymocytes to thymic stroma.

Properties

Applications

Our Abpromise guarantee covers the use of ab25272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Celluar Activation Use at an assay dependent concentration.

In vitro T cells activation: Use at an assay dependent dilution

Functional Studies Use at an assay dependent concentration.

Induction of apoptosis: Use at as assay dependent dilution

Flow Cyt Use 0.2µg for 106 cells.
IHC-Fr Use at an assay dependent concentration.

Use at an assay dependent dilution

Target

  • FunctionMay play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
  • Sequence similaritiesContains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD7 antibody
    • CD90 antibody
    • CD90 antigen antibody
    • CDw90 antibody
    • FLJ33325 antibody
    • MGC128895 antibody
    • T25 antibody
    • Theta antigen antibody
    • Thy 1 antibody
    • Thy 1 cell surface antigen antibody
    • Thy 1 membrane glycoprotein antibody
    • Thy 1 T cell antigen antibody
    • Thy 1.2 antibody
    • Thy-1 antigen antibody
    • Thy-1 membrane glycoprotein antibody
    • Thy1 antibody
    • Thy1 antigen antibody
    • Thy1 T cell antigen antibody
    • Thy1.1 antibody
    • Thy1.2 antibody
    • THY1_HUMAN antibody
    • Thymus cell antigen 1, theta antibody
    see all

References for Anti-CD90 / Thy1 antibody [G7] (PE/Cy5®) (ab25272)

This product has been referenced in:
  • Hueber AO  et al. Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism. J Exp Med 179:785-96 (1994). Read more (PubMed: 7906706) »
  • Ucker DS  et al. Activation-driven T cell death. II. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death. J Immunol 149:1583-92 (1992). Read more (PubMed: 1380534) »

See all 6 Publications for this product

Product Wall

Thank you for your enquiry. I have been in correspondence with the source of this antibody and unfortunately they in turn source this antibody. They have informed me that they have not been provided with details of the immunogen from their originat...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"