Anti-CD90 / Thy1 antibody [G7] (Phycoerythrin) (ab24904)

Overview

  • Product name
    Anti-CD90 / Thy1 antibody [G7] (Phycoerythrin)
    See all CD90 / Thy1 primary antibodies
  • Description
    Rat monoclonal [G7] to CD90 / Thy1 (Phycoerythrin)
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Specificity
    ab24904 is specific for Thy 1.1 and Thy 1.2 alloantigens (Thy 1 epitope region A).
  • Tested applications
    Suitable for: Functional Studies, Flow Cyt, IHC-Fr, Cellular Activationmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Epitope
    Thy 1 epitope region A
  • General notes


    ab24904 stimulates T-cell proliferation and IL2 secretion, via signalling through the T-cell receptor/CD3 complex. ab24904 has also been reported to promote apoptosis of thymocytes and CTL clones and to mediate adhesion of thymocytes to thymic stroma.

Properties

Applications

Our Abpromise guarantee covers the use of ab24904 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.

Induction of apoptosis.

Flow Cyt Use 2µg for 106 cells.

ab154450 - Rat monoclonal IgG2c, is suitable for use as an isotype control with this antibody.

IHC-Fr Use at an assay dependent concentration.
Cellular Activation Use at an assay dependent concentration.

Target

  • Function
    May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
  • Sequence similarities
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD7 antibody
    • CD90 antibody
    • CD90 antigen antibody
    • CDw90 antibody
    • FLJ33325 antibody
    • MGC128895 antibody
    • T25 antibody
    • Theta antigen antibody
    • Thy 1 antibody
    • Thy 1 cell surface antigen antibody
    • Thy 1 membrane glycoprotein antibody
    • Thy 1 T cell antigen antibody
    • Thy 1.2 antibody
    • Thy-1 antigen antibody
    • Thy-1 membrane glycoprotein antibody
    • Thy1 antibody
    • Thy1 antigen antibody
    • Thy1 T cell antigen antibody
    • Thy1.1 antibody
    • Thy1.2 antibody
    • THY1_HUMAN antibody
    • Thymus cell antigen 1, theta antibody
    see all

Images

  • Flow cytometry analysis staining CD90 / Thy1 in mouse splenocytes using ab24904 at a dilution of 0.03 μg/106 cells.

References

This product has been referenced in:
  • Tingling JD  et al. CD24 expression identifies teratogen-sensitive fetal neural stem cell subpopulations: evidence from developmental ethanol exposure and orthotopic cell transfer models. PLoS One 8:e69560 (2013). Flow Cyt ; Mouse . Read more (PubMed: 23894503) »
  • Hueber AO  et al. Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism. J Exp Med 179:785-96 (1994). Read more (PubMed: 7906706) »

See all 6 Publications for this product

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