Overview

  • Product nameAnti-CDC11 antibody
  • Description
    Rabbit polyclonal to CDC11
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Saccharomyces cerevisiae
  • Immunogen

    Synthetic peptide derived from the C terminal domain of CDC11

Properties

Applications

Our Abpromise guarantee covers the use of ab66452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
WB 1/500 - 1/5000. Predicted molecular weight: 48 kDa.

Target

  • RelevanceCDC11 is a component of Septins. Septins are GTPases involved in cytokinesis. They assemble early in the cell cycle as a patch at the incipient bud site and form a ring approximate 15 minutes before bud emergence. This then transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck. This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck. The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Many proteins bind assymetrically to the septin collar. The septin assembly is regulated by protein kinases GIN4 and/or CLA4. Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation.
  • Cellular localizationMembrane. Bud neck. Note: Present at the bud neck during cell division.
  • Database links
    • Alternative names
      • Cell division control protein 11 antibody
      • PSL9 antibody

    References for Anti-CDC11 antibody (ab66452)

    ab66452 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"