The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ab204870 (Cdc25C peptide) can be utilized as a substrate for the active protein kinase ab105126 (Active human GRK1 full length protein)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
Cell division cycle 25 homolog C
Cell division cycle 25C
Cell division cycle 25C protein
Dual specificity phosphatase Cdc25C
M phase inducer phosphatase 3
M-phase inducer phosphatase 3
Mitosis inducer CDC25
protein phosphatase 1, regulatory subunit 60
Functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It directly dephosphorylates CDK1 and activate its kinase activity.
Belongs to the MPI phosphatase family. Contains 1 rhodanese domain.
Expressed predominantly in G2 phase.
Phosphorylated by CHK1 on Ser-216. This phosphorylation creates a binding site for 14-3-3 protein and inhibits the phosphatase. Phosphorylated by PLK4.