• Product name
    Anti-Cdc37 antibody [EPR4934]
    See all Cdc37 primary antibodies
  • Description
    Rabbit monoclonal [EPR4934] to Cdc37
  • Tested applications
    Suitable for: WB, IP, IHC-P, Flow Cytmore details
    Unsuitable for: ICC
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human Cdc37.

  • Positive control
    • Jurkat, A431, K562, LnCaP and SW480 cell lysates; Human breast ductal infiltrating carcinoma
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents


Associated products


Our Abpromise guarantee covers the use of ab109419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 44 kDa).
IP 1/10 - 1/100.
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • Application notes
    Is unsuitable for ICC.
  • Target

    • Function
      Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
    • Sequence similarities
      Belongs to the CDC37 family.
    • Post-translational
      Constitutively sumoylated by UBE2I.
    • Cellular localization
    • Information by UniProt
    • Database links
    • Alternative names
      • CDC 37 antibody
      • Cdc37 antibody
      • CDC37 cell division cycle 37 homolog antibody
      • CDC37 cell division cycle 37 S cerevisiae homolog antibody
      • CDC37 cell division cycle 37, S cerevisiae, homolog of antibody
      • Cdc37 homolog antibody
      • CDC37 protein antibody
      • CDC37_HUMAN antibody
      • CDC37A antibody
      • cell division cycle 37 antibody
      • Cell division cycle 37 homolog antibody
      • Hsp90 chaperone protein kinase targeting subunit antibody
      • Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody
      • Hsp90 chaperone protein kinase-targeting subunit antibody
      • Hsp90 co chaperone Cdc37 antibody
      • Hsp90 co-chaperone Cdc37 antibody
      • p50 antibody
      • p50Cdc37 antibody
      • S cerevisiae hypothetical protein CDC37 antibody
      see all

    Anti-Cdc37 antibody [EPR4934] images

    • All lanes : Anti-Cdc37 antibody [EPR4934] (ab109419) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : A431 cell lysate
      Lane 3 : K562 cell lysate
      Lane 4 : LnCaP cell lysate
      Lane 5 : SW480 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 44 kDa
    • ab109419, at 1/250 dilution, staining Cdc37 in Human breast ductal infiltrating carcinoma by Immunohistochemistry.

    References for Anti-Cdc37 antibody [EPR4934] (ab109419)

    This product has been referenced in:
    • Synoradzki K & Bieganowski P Middle domain of human Hsp90 isoforms differentially binds Aha1 in human cells and alters Hsp90 activity in yeast. Biochim Biophys Acta 1853:445-52 (2015). Read more (PubMed: 25486457) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab109419.
    Please use the links above to contact us or submit feedback about this product.


    Sign up