Anti-Cdc37 antibody - N-terminal (ab166723)

Overview

  • Product name
    Anti-Cdc37 antibody - N-terminal
    See all Cdc37 primary antibodies
  • Description
    Rabbit polyclonal to Cdc37 - N-terminal
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to N terminal amino acids of Human Cdc37 (NP_008996.1 ).

  • Positive control
    • MCF7 and COS7 cell extracts; Human Small Intestine, Submucosal Plexus tissue; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab166723 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 44 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.

Target

  • Function
    Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
  • Sequence similarities
    Belongs to the CDC37 family.
  • Post-translational
    modifications
    Constitutively sumoylated by UBE2I.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CDC 37 antibody
    • Cdc37 antibody
    • CDC37 cell division cycle 37 homolog antibody
    • CDC37 cell division cycle 37 S cerevisiae homolog antibody
    • CDC37 cell division cycle 37, S cerevisiae, homolog of antibody
    • Cdc37 homolog antibody
    • CDC37 protein antibody
    • CDC37_HUMAN antibody
    • CDC37A antibody
    • cell division cycle 37 antibody
    • Cell division cycle 37 homolog antibody
    • Hsp90 chaperone protein kinase targeting subunit antibody
    • Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody
    • Hsp90 chaperone protein kinase-targeting subunit antibody
    • Hsp90 co chaperone Cdc37 antibody
    • Hsp90 co-chaperone Cdc37 antibody
    • p50 antibody
    • p50Cdc37 antibody
    • S cerevisiae hypothetical protein CDC37 antibody
    see all

Images

  • All lanes : Anti-Cdc37 antibody - N-terminal (ab166723) at 1/500 dilution

    Lane 1 : MCF7 cell extracts
    Lane 2 : COS7 cell extracts
    Lane 3 : COS7 cell extracts with synthesized peptide


    Predicted band size : 44 kDa
  • Immunohistochemical analysis of Formalin-Fixed, Paraffin-Embedded Human Small Intestine Submucosal Plexus tissue labeling Cdc37 with ab166723 at 5 µg/ml.
  • Immunofluorescent analysis of HeLa cells labeling Cdc37 with ab166723 at 1/100 dilution. The image on the right is treated with the synthesized peptide.

References

ab166723 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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