Anti-CDC42 binding protein kinase alpha antibody (ab113710)

Overview

  • Product nameAnti-CDC42 binding protein kinase alpha antibody
    See all CDC42 binding protein kinase alpha primary antibodies
  • Description
    Goat polyclonal to CDC42 binding protein kinase alpha
  • Tested applicationsSuitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide (

    SGEVRLRQLEQFI

    -C) corresponding to N terminal amino acids 2-14 of Human CDC42 binding protein kinase alpha.

  • Positive control
    • Human Brain Cerebellum and Human Small Intestine Submucosal Plexus tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab113710 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/16000.
IHC-P Use a concentration of 3.75 µg/ml.

Target

  • FunctionMay act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.
  • Tissue specificityAbundant in the heart, brain, skeletal muscle, kidney, and pancreas, with little or no expression in the lung and liver.
  • Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 CNH domain.
    Contains 1 CRIB domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 protein kinase domain.
  • Cellular localizationCytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent.
  • Information by UniProt
  • Database links
  • Alternative names
    • A930014J19Rik antibody
    • CDC42 binding protein kinase alpha (DMPK like) antibody
    • CDC42 binding protein kinase alpha antibody
    • CDC42 binding protein kinase alpha dmpk like antibody
    • CDC42 binding protein kinase beta antibody
    • CDC42-binding protein kinase alpha antibody
    • CDC42BPA antibody
    • DKFZp686L1738 antibody
    • DKFZp686P1738 antibody
    • DMPK like antibody
    • DMPK-like alpha antibody
    • FLJ23347 antibody
    • KIAA0451 antibody
    • MGC189823 antibody
    • MRCK alpha antibody
    • mrck antibody
    • mrcka antibody
    • MRCKA_HUMAN antibody
    • Myotonic dystrophy kinase related CDC42 binding protein kinase alpha antibody
    • Myotonic dystrophy kinase-related CDC42-binding kinase alpha antibody
    • Myotonic dystrophy protein kinase-like alpha antibody
    • OTTHUMP00000035727 antibody
    • OTTHUMP00000035728 antibody
    • OTTHUMP00000035729 antibody
    • OTTHUMP00000035730 antibody
    • pk428 antibody
    • RP5-1087E8.4 antibody
    • Ser thr protein kinase PK428 antibody
    • Ser thr protein kinase related to the myotonic dystrophy protein kinase antibody
    • Serine/threonine protein kinase MRCK alpha antibody
    • Serine/threonine-protein kinase MRCK alpha antibody
    see all

Anti-CDC42 binding protein kinase alpha antibody images

  • ab113710 at 3.75 µg/ml staining CDC42 binding protein kinase alpha in Formalin-Fixed, Paraffin-Embedded Human brain cerebellum tissue.
  • ab113710 at 3.75 µg/ml staining CDC42 binding protein kinase alpha in Formalin-Fixed, Paraffin-Embedded Human small intestine, submucosal plexus tissue.

References for Anti-CDC42 binding protein kinase alpha antibody (ab113710)

ab113710 has not yet been referenced specifically in any publications.

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