Anti-CDC42 binding protein kinase alpha antibody (ab56479)

Overview

  • Product nameAnti-CDC42 binding protein kinase alpha antibody
    See all CDC42 binding protein kinase alpha primary antibodies
  • Description
    Mouse monoclonal to CDC42 binding protein kinase alpha
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment: LVQASERLKN QSKELKDAHC QRKLAMQEFM EINERLTELH TQKQKLARHV RDKEEEVDLV MQKVESLRQE LRRTERAKKE LEVHTEALAA EASKDRKLRE , corresponding to amino acids 551-650 of Human CDC42 binding protein kinase alpha

Properties

Applications

Our Abpromise guarantee covers the use of ab56479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.
    • Tissue specificityAbundant in the heart, brain, skeletal muscle, kidney, and pancreas, with little or no expression in the lung and liver.
    • Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 CNH domain.
      Contains 1 CRIB domain.
      Contains 1 PH domain.
      Contains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 protein kinase domain.
    • Cellular localizationCytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent.
    • Information by UniProt
    • Database links
    • Alternative names
      • A930014J19Rik antibody
      • CDC42 binding protein kinase alpha (DMPK like) antibody
      • CDC42 binding protein kinase alpha antibody
      • CDC42 binding protein kinase alpha dmpk like antibody
      • CDC42 binding protein kinase beta antibody
      • CDC42-binding protein kinase alpha antibody
      • CDC42BPA antibody
      • DKFZp686L1738 antibody
      • DKFZp686P1738 antibody
      • DMPK like antibody
      • DMPK-like alpha antibody
      • FLJ23347 antibody
      • KIAA0451 antibody
      • MGC189823 antibody
      • MRCK alpha antibody
      • mrck antibody
      • mrcka antibody
      • MRCKA_HUMAN antibody
      • Myotonic dystrophy kinase related CDC42 binding protein kinase alpha antibody
      • Myotonic dystrophy kinase-related CDC42-binding kinase alpha antibody
      • Myotonic dystrophy protein kinase-like alpha antibody
      • OTTHUMP00000035727 antibody
      • OTTHUMP00000035728 antibody
      • OTTHUMP00000035729 antibody
      • OTTHUMP00000035730 antibody
      • pk428 antibody
      • RP5-1087E8.4 antibody
      • Ser thr protein kinase PK428 antibody
      • Ser thr protein kinase related to the myotonic dystrophy protein kinase antibody
      • Serine/threonine protein kinase MRCK alpha antibody
      • Serine/threonine-protein kinase MRCK alpha antibody
      see all

    References for Anti-CDC42 binding protein kinase alpha antibody (ab56479)

    ab56479 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56479.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"