Anti-CDC42 binding protein kinase alpha antibody (ab95880)

Overview

  • Product nameAnti-CDC42 binding protein kinase alpha antibody
    See all CDC42 binding protein kinase alpha primary antibodies
  • Description
    Rabbit polyclonal to CDC42 binding protein kinase alpha
  • Tested applicationsIPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Dog, Rhesus monkey, Chinese Hamster, Orangutan, Bat
  • Immunogen

    A region between residue 1560 and 1610 of human CDC42 binding protein kinase alpha using the numbering given in entry (CAH71185.1)

  • Positive control
    • HeLa cytoplasmic lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab95880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionMay act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.
    • Tissue specificityAbundant in the heart, brain, skeletal muscle, kidney, and pancreas, with little or no expression in the lung and liver.
    • Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 CNH domain.
      Contains 1 CRIB domain.
      Contains 1 PH domain.
      Contains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 protein kinase domain.
    • Cellular localizationCytoplasm. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent.
    • Information by UniProt
    • Database links
    • Alternative names
      • A930014J19Rik antibody
      • CDC42 binding protein kinase alpha (DMPK like) antibody
      • CDC42 binding protein kinase alpha antibody
      • CDC42 binding protein kinase alpha dmpk like antibody
      • CDC42 binding protein kinase beta antibody
      • CDC42-binding protein kinase alpha antibody
      • CDC42BPA antibody
      • DKFZp686L1738 antibody
      • DKFZp686P1738 antibody
      • DMPK like antibody
      • DMPK-like alpha antibody
      • FLJ23347 antibody
      • KIAA0451 antibody
      • MGC189823 antibody
      • MRCK alpha antibody
      • mrck antibody
      • mrcka antibody
      • MRCKA_HUMAN antibody
      • Myotonic dystrophy kinase related CDC42 binding protein kinase alpha antibody
      • Myotonic dystrophy kinase-related CDC42-binding kinase alpha antibody
      • Myotonic dystrophy protein kinase-like alpha antibody
      • OTTHUMP00000035727 antibody
      • OTTHUMP00000035728 antibody
      • OTTHUMP00000035729 antibody
      • OTTHUMP00000035730 antibody
      • pk428 antibody
      • RP5-1087E8.4 antibody
      • Ser thr protein kinase PK428 antibody
      • Ser thr protein kinase related to the myotonic dystrophy protein kinase antibody
      • Serine/threonine protein kinase MRCK alpha antibody
      • Serine/threonine-protein kinase MRCK alpha antibody
      see all

    Anti-CDC42 binding protein kinase alpha antibody images

    • Detection of Human CDC42 binding protein kinase alpha by Immunoprecipitation, using ab95880 at 3µg/mg lysate. Image shows immunoprecipitated CDC42 binding protein kinase alpha detected with post IP WB, loading 20% of IP and using HeLa whole cell lysate at 1mg, with a95880 at 1 µg/ml in lane 1, an antibody recognising a downstream epitope in lane 2 and control IgG in lane 3. Detection: Chemiluminescence with an exposure time of 10 seconds.

    References for Anti-CDC42 binding protein kinase alpha antibody (ab95880)

    ab95880 has not yet been referenced specifically in any publications.

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