Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionProbably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Tissue specificityHighly expressed in the heart. Weakly expressed in the pancreas and liver.
Sequence similaritiesBelongs to the BORG/CEP family. Contains 1 CRIB domain.
DomainThe CRIB domain mediates interaction with CDC42.