The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 38 kDa).
FunctionProbably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.
Tissue specificityNot detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues.
Sequence similaritiesBelongs to the BORG/CEP family. Contains 1 CRIB domain.