Overview

  • Product name
  • Description
    Mouse polyclonal to CDC42EP4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length CDC42EP4 protein (Human)

  • Positive control
    • CDC42EP4 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67780 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 38 kDa).

Target

  • Function
    Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.
  • Tissue specificity
    Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues.
  • Sequence similarities
    Belongs to the BORG/CEP family.
    Contains 1 CRIB domain.
  • Cellular localization
    Endomembrane system. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • Binder of Rho GTPases 4 antibody
    • BORG4 antibody
    • BORG4_HUMAN antibody
    • CDC42 effector protein (Rho GTPase binding) 4 antibody
    • Cdc42 effector protein 4 antibody
    • CDC42EP4 antibody
    • CEP4 antibody
    see all

Images

  • All lanes : Anti-CDC42EP4 antibody (ab67780) at 1/500 dilution

    Lane 1 : CDC42EP4 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 38 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)

References

ab67780 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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