• Product name
    Anti-CDC45L antibody [EPR5758]
    See all CDC45L primary antibodies
  • Description
    Rabbit monoclonal [EPR5758] to CDC45L
  • Tested applications
    Suitable for: WB, IHC-P, ICC, Flow Cytmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human CDC45L.

  • Positive control
    • HeLa, Jurkat, K562, and 293T cell lysates. Human kidney tissue
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.



Our Abpromise guarantee covers the use of ab108350 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Detects a band of approximately 65 kDa (predicted molecular weight: 66 kDa).
IHC-P 1/50 - 1/100. Perform antigen retrieval before commencing with IHC staining protocol
ICC 1/50 - 1/100.
Flow Cyt 1/500 - 1/1000. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function
      Required for initiation of chromosomal DNA replication.
    • Tissue specificity
      Widely expressed, highest levels are found in adult testis and thymus and in fetal liver.
    • Sequence similarities
      Belongs to the CDC45 family.
    • Developmental stage
      Transcript peaks at G1-S transition, but total protein remains constant throughout the cell cycle. Expressed in multiple tissues during embryogenesis, including neural crest-derived structures.
    • Cellular localization
      Cytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • CDC 45 antibody
      • CDC 45L antibody
      • CDC45 (cell division cycle 45, S.cerevisiae homolog) like antibody
      • CDC45 antibody
      • CDC45 cell division cycle 45 like antibody
      • CDC45 like antibody
      • CDC45 related protein antibody
      • CDC45_HUMAN antibody
      • CDC45L2 antibody
      • Cell division control protein 45 homolog antibody
      • Cell division cycle 45 like 2 antibody
      • Cell division cycle 45 like antibody
      • PORC PI 1 antibody
      • PORC-PI-1 antibody
      see all

    Anti-CDC45L antibody [EPR5758] images

    • All lanes : Anti-CDC45L antibody [EPR5758] (ab108350) at 1/10000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : K562 cell lysate
      Lane 4 : 293T cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 66 kDa
    • Immunohistochemical analysis of paraffin-embedded Human kidney tissue using ab108350 at 1/50
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References for Anti-CDC45L antibody [EPR5758] (ab108350)

    This product has been referenced in:
    • Anantha RW  et al. Requirement of heterogeneous nuclear ribonucleoprotein C for BRCA gene expression and homologous recombination. PLoS One 8:e61368 (2013). WB . Read more (PubMed: 23585894) »

    See 1 Publication for this product

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