Recombinant
RabMAb

Anti-Cdc6 (phospho S106) antibody [EPR761(2)] (ab76422)

Overview

  • Product name
    Anti-Cdc6 (phospho S106) antibody [EPR761(2)]
    See all Cdc6 primary antibodies
  • Description
    Rabbit monoclonal [EPR761(2)] to Cdc6 (phospho S106)
  • Specificity
    The antibody only detects Cdc6 phosphorylated on Serine 106.
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic phosphopeptide corresponding to residues surrounding Serine 106 of human Cdc6

  • Positive control
    • Raji cell lysate treated with FBS
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab76422 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 63 kDa (predicted molecular weight: 63 kDa).Can be blocked with Cdc6 (phospho S106) peptide (ab197758).
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function
      Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
    • Sequence similarities
      Belongs to the CDC6/cdc18 family.
    • Cellular localization
      Nucleus. Cytoplasm. The protein is nuclear in G1 and cytoplasmic in S-phase cells.
    • Information by UniProt
    • Database links
    • Alternative names
      • Cdc 18L antibody
      • Cdc 6 antibody
      • CDC18 (cell division cycle 18, S.pombe, homolog) like antibody
      • CDC18 (S.pombe) antibody
      • Cdc18 related protein antibody
      • CDC18(S.pombe) antibody
      • Cdc18-related protein antibody
      • Cdc18L antibody
      • cdc6 antibody
      • CDC6 cell division cycle 6 homolog antibody
      • CDC6 related protein antibody
      • CDC6-related protein antibody
      • CDC6_HUMAN antibody
      • Cdc6p antibody
      • CELL CYCLE CONTROLLER CDC6 antibody
      • Cell division control protein 6 antibody
      • Cell division control protein 6 homolog antibody
      • Cell division cycle 6 homolog (S. cerevisiae) antibody
      • Cell division cycle 6 homolog antibody
      • Cell division cycle 6, S. cerevisiae, homolog of antibody
      • HsCDC 6 antibody
      • HsCDC18 antibody
      • HsCDC6 antibody
      • p62 antibody
      • p62(cdc 6) antibody
      • p62(cdc6) antibody
      see all

    Anti-Cdc6 (phospho S106) antibody [EPR761(2)] images

    • All lanes : Anti-Cdc6 (phospho S106) antibody [EPR761(2)] (ab76422) at 1/2000 dilution

      Lane 1 : Raji cell lysate
      Lane 2 : Raji cell lysate treated with FBS

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/1000 dilution

      Predicted band size : 63 kDa
      Observed band size : 63 kDa

    References for Anti-Cdc6 (phospho S106) antibody [EPR761(2)] (ab76422)

    This product has been referenced in:
    • Betts JF  et al. D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine. Front Synaptic Neurosci 6:11 (2014). IF . Read more (PubMed: 24822045) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab76422.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up