Overview

  • Product name
  • Description
    Rabbit polyclonal to CDCA4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide: SSAWEMDGPR ENRGSFHKSL DQIFETLETK NPSCMEELFS DVDSPYYDLD , corresponding to a region within internal sequence amino acids 143-192 of Human CDCA4 (NP_060425).

  • Positive control
    • COLO205 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab107944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May participate in the regulation of cell proliferation through the E2F/RB pathway. May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation.
  • Tissue specificity
    Highest levels of expression in the pancreas, thymus, testis, spleen, liver, placenta and leukocytes. Relatively low levels in the lung, kidney, prostate, ovary, small intestine and colon. Hardly detectable, if at all, in the brain, skeletal muscle and heart.
  • Sequence similarities
    Contains 1 SERTA domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CDCA 4 antibody
    • Cdca4 antibody
    • CDCA4_HUMAN antibody
    • Cell division cycle associated 4 antibody
    • Cell division cycle-associated protein 4 antibody
    • FLJ20764 antibody
    • FLJ52878 antibody
    • Hematopoietic progenitor protein antibody
    • Hepp antibody
    • MGC19517 antibody
    • SEI 3 antibody
    • SEI-3/HEPP antibody
    • SEI3 antibody
    see all

Images

  • Anti-CDCA4 antibody (ab107944) at 1 µg/ml + COLO205 Cell Lysate at 10 µg

    Predicted band size : 26 kDa

References

This product has been referenced in:
  • Li C  et al. Nutrient/serum starvation derived TRIP-Br3 down-regulation accelerates apoptosis by destabilizing XIAP. Oncotarget 6:7522-35 (2015). WB, IP, IF . Read more (PubMed: 25691055) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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