• Product name
  • Description
    Rabbit polyclonal to CDCA7L
  • Tested applications
    Suitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residue 400 and the C-terminus (residue 454) of Human CDCA7L (NP_061189.2)

  • Positive control
    • Whole cell lysates from HeLa and 293T cells.



Our Abpromise guarantee covers the use of ab70637 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Detects a band of approximately 53 kDa (predicted molecular weight: 53 kDa).
IP Use at 2-5 µg/mg of lysate.


  • Relevance
    CDCA7L is a member of the CDCA (cell division cycle associated) protein family. Members of this family have expression patterns associated with other known cell cycle genes such as cyclins and CDC genes. CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It is involved in apoptotic signaling pathways and may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
  • Cellular localization
    Cytoplasm. Nucleus. Note: associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
  • Database links
  • Alternative names
    • c Myc Interacting protein JPO2 antibody
    • CDCA7L antibody
    • DKFZp762L0311 antibody
    • HR1 antibody
    • JPO2 antibody
    • Protein JPO2 antibody
    • R1 antibody
    • RAM2 antibody
    • Transcription Factor RAM2 antibody
    see all

Anti-CDCA7L antibody images

  • All lanes : Anti-CDCA7L antibody (ab70637) at 0.04 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg
    Lane 4 : 293T whole cell lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 53 kDa
    Observed band size : 53 kDa
    Additional bands at : 110 kDa,130 kDa,70 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 30 seconds
  • Detection of CDCA7L by Western Blot of Immunprecipitate. ab70637 at 1µg/ml staining CDCA7L in HeLa whole cell lysate immunoprecipitated using ab70637 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: chemiluminescence with exposure time of 30 seconds.

References for Anti-CDCA7L antibody (ab70637)

ab70637 has not yet been referenced specifically in any publications.

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