Overview

  • Product nameAnti-CDK1 antibody [E53]See all CDK1 primary antibodies ...
  • Description
    Rabbit monoclonal [E53] to CDK1
  • Tested applicationsWB, IPmore details
  • Species reactivity
    Reacts with: Human

    Does not react with

    Mouse, Rat
  • Immunogen

    Synthetic peptide (Human).

  • Positive control
    • WB: Hela cell lysate.
  • General notes

    Produced under U.S. Patent No. 5,675,063.

     

    A trial size is available for this product.

Properties

Applications

Our Abpromise guarantee covers the use of ab32030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IP
  • Application notesIP: 1/40.
    WB: 1/5000. Detects a band of approximately 35 kDa (predicted molecular weight: 34 kDa).

    Is unsuitable for FACS, ICC or IHC.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPlays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
    • Tissue specificityIsoform 2 is found in breast cancer tissues.
    • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
      Contains 1 protein kinase domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • FormCDK1 can be located to the Nucleus, cytoplasm and Mithocondria. It's cytoplasmic during interphase and reversibly translocated from cytoplasm to the nucleus when phosphorilated before G2-M transition when associated with cyclin-B1. Accumulates in mitochondria in G2-arrested cells upon DNA-damage.
    • Alternative names
      • Cdc 2 antibody
      • Cdc2 antibody
      • CDC28A antibody
      • CDK 1 antibody
      • CDK1 antibody
      • CDK1_HUMAN antibody
      • CDKN1 antibody
      • CELL CYCLE CONTROLLER CDC2 antibody
      • Cell division control protein 2 antibody
      • Cell division control protein 2 homolog antibody
      • Cell division cycle 2 G1 to S and G2 to M antibody
      • Cell division protein kinase 1 antibody
      • Cell Divsion Cycle 2 Protein antibody
      • Cyclin Dependent Kinase 1 antibody
      • Cyclin-dependent kinase 1 antibody
      • DKFZp686L20222 antibody
      • MGC111195 antibody
      • p34 Cdk1 antibody
      • p34 Protein Kinase antibody
      • P34CDC2 antibody
      see all

    Anti-CDK1 antibody [E53] images

    References for Anti-CDK1 antibody [E53] (ab32030)

    ab32030 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"