Overview

  • Product nameAnti-Cdk5 antibody [8A1]
    See all Cdk5 primary antibodies
  • Description
    Mouse monoclonal [8A1] to Cdk5
  • Specificityab28438 recognises Cyclin-dependentkinase-5 (CDK5).
  • Tested applicationsSuitable for: ELISA, WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein (Human) His tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells

  • Positive control
    • SH-SY5Y cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab28438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
IP
  • Application notesELISA: Use at an assay dependent dilution.
    IP: Use at a concentration of 2 µg/ml cell lysate.
    WB: 1/1000 - 1/2000. Detects a band of approximately 32 kDa (predicted molecular weight: 33 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionProbably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
    • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
      Contains 1 protein kinase domain.
    • Cellular localizationCytoplasm. Cell projection > lamellipodium. Cell projection > growth cone. In axonal growth cone with extension to the peripheral lamellipodia.
    • Information by UniProt
    • Database links
    • Alternative names
      • Cdk 5 antibody
      • Cdk5 antibody
      • CDK5_HUMAN antibody
      • Cell division protein kinase 5 antibody
      • Crk6 antibody
      • Cyclin dependent kinase 5 antibody
      • Cyclin-dependent kinase 5 antibody
      • Protein kinase CDK5 splicing antibody
      • PSSALRE antibody
      • Serine threonine protein kinase PSSALRE antibody
      • Serine/threonine-protein kinase PSSALRE antibody
      • Tau protein kinase II catalytic subunit antibody
      • TPKII catalytic subunit antibody
      see all

    Anti-Cdk5 antibody [8A1] images

    • All lanes : Anti-Cdk5 antibody [8A1] (ab28438) at 1/1000 dilution

      Lane 1 : SH-SY5Y cell lysates
      Lane 2 : SK-N-SH cell lysates
      Lane 3 : Mouse brain tissues


      Predicted band size : 33 kDa
      Observed band size : 32 kDa (why is the actual band size different from the predicted?)

    References for Anti-Cdk5 antibody [8A1] (ab28438)

    ab28438 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab28438.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"