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Goat polyclonal to CDKN1A interacting zinc finger protein 1
ab177238 is expected to recognize all reported isoforms (NP_036259.2; NP_001124487.1; NP_001124489.1; NP_001124490.1; NP_001244904.1; NP_001244905.1). Reported variants represent identical protein: NP_036259.2, NP_001124488.1.
Synthetic peptide corresponding to Human CDKN1A interacting zinc finger protein 1 aa 869-883 (C terminal) (Cysteine residue).
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
Immunogen affinity purified
ab177238 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 100 kDa).
May regulate the subcellular localization of CIP/WAF1.
Involvement in disease
Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk.
Contains 1 matrin-type zinc finger.
Information by UniProt
CDKN1A-interacting zinc finger protein 1 antibody
Cip1-interacting zinc finger protein antibody
Western blot - Anti-CDKN1A interacting zinc finger protein 1 antibody (ab177238)
Anti-CDKN1A interacting zinc finger protein 1 antibody (ab177238) at 0.3 µg/ml + Hela nuclear lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size:
Observed band size:
90 kDa (
why is the actual band size different from the predicted?
Primary incubation was 1 hour.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"