Overview

  • Product name
    Anti-CDKN2A/p19ARF antibody
    See all CDKN2A/p19ARF primary antibodies
  • Description
    Goat polyclonal to CDKN2A/p19ARF
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide:

    C-RRGPHRNPGPGDDD

    with a Cysteine residue linker, corresponding to internal sequence amino acids 54-67 of Mouse CDKN2A/p19ARF (NP_034007.1).

  • Positive control
    • Mouse kidney and liver lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab126879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 18 kDa (predicted molecular weight: 19 kDa).

Target

  • Relevance
    The gene for CDK2NA generates several transcripts/proteins which differ from each other in their first exons. Three of these transcripts are generated by alternative splicing (isoform 1 a.k.a p16INK4A, isoform 2 and isoform 3 a.k.a p12), two of which are known to function as inhibitors of CDK4 kinase. One other transcript that is generated from this gene contains an alternate reading frame (ARF), with the first exon located 20kb upstream of the remainder of the gene(isoform 4 a.k.a. p14ARF, p19ARF, ARF). In spite of the structural and some functional differences, all the proteins encoded by the CDKN2A gene are involved in cell cycle G1 control.
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • ARF antibody
    • CDKN2A antibody
    • Cyclin dependent kinase inhibitor 2A antibody
    • INK4 antibody
    • MTS1 antibody
    • P19 antibody
    see all

Images

  • Anti-CDKN2A/p19ARF antibody (ab126879) at 0.3 µg/ml + Mouse liver lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 19 kDa

References

ab126879 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab126879.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up