Overview

  • Product nameAnti-CDX2 antibody [SP54]
    See all CDX2 primary antibodies
  • Description
    Rabbit monoclonal [SP54] to CDX2
  • Tested applicationsSuitable for: IHC-P, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    A synthetic peptide corresponding to N-terminal region of Human CDX2.

  • Positive control
    • Human Colon carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab101532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Antigen retrieval is recommended: Boil tissue section in 10mM Citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.
Flow Cyt Use at an assay dependent concentration. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • FunctionInvolved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
  • Sequence similaritiesBelongs to the Caudal homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Post-translational
    modifications
    Phosphorylation of Ser-60 mediates the transactivation capacity.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Caudal type homeo box 2 antibody
    • Caudal type homeo box transcription factor 2 antibody
    • Caudal type homeobox 2 antibody
    • Caudal type homeobox protein 2 antibody
    • Caudal type homeobox transcription factor 2 antibody
    • Caudal-type homeobox protein 2 antibody
    • CDX 2 antibody
    • CDX 3 antibody
    • CDX-3 antibody
    • Cdx2 antibody
    • CDX2_HUMAN antibody
    • CDX3 antibody
    • Homeobox protein CDX 2 antibody
    • Homeobox protein CDX-2 antibody
    see all

Anti-CDX2 antibody [SP54] images

  • Flow cytometric analysis of rabbit anti-CDX2 (SP54) antibody ab101532(1/100) in HT29 cells (green) compared to negative control of rabbit IgG (blue).

  • Staining of Human CDX2 in a Formalin/PFA-fixed paraffin-embedded section of Human Colon Carcinoma using ab101532 at a dilution of 1/100.

References for Anti-CDX2 antibody [SP54] (ab101532)

This product has been referenced in:
  • Chen Y  et al. 5-Aza-dC treatment induces mesenchymal-to-epithelial transition in 1st trimester trophoblast cell line HTR8/SVneo. Biochem Biophys Res Commun 432:116-22 (2013). ICC/IF ; Human . Read more (PubMed: 23376068) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"