Overview

  • Product nameAnti-CEBP Beta antibody
    See all CEBP Beta primary antibodies
  • Description
    Rabbit polyclonal to CEBP Beta
  • Specificityab53138 detects endogenous levels of total CEBP Beta protein.
  • Tested applicationsSuitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic non-phosphopeptide derived from human CEBP Beta around the phosphorylation site of threonine 235 (P-G-T-P-S).

  • Positive control
    • NIH/3T3 cell extracts and human lung carcinoma tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab53138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/300 - 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
IHC-P Use at an assay dependent concentration.
ELISA 1/10000.

Target

  • FunctionImportant transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation.
  • Tissue specificityExpressed at low levels in the lung, kidney and spleen.
  • Sequence similaritiesBelongs to the bZIP family. C/EBP subfamily.
    Contains 1 bZIP domain.
  • Domainthe 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
  • Post-translational
    modifications
    Sumoylated by polymeric chains of SUMO2 or SUMO3.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AGP/EBP antibody
    • C EBP beta antibody
    • C/EBP beta antibody
    • C/EBP related protein 2 antibody
    • CCAAT Enhancer Binding Protein beta antibody
    • CCAAT/enhancer-binding protein beta antibody
    • CEBPB antibody
    • CEBPB_HUMAN antibody
    • CRP2 antibody
    • IL 6DBP antibody
    • IL6DBP antibody
    • Interleukin 6 dependent binding protein antibody
    • LAP antibody
    • Liver activator protein antibody
    • Liver enriched transcriptional activator antibody
    • NF IL6 antibody
    • NFIL6 antibody
    • Nuclear factor NF IL6 antibody
    • Nuclear factor NF-IL6 antibody
    • SF B antibody
    • SFB antibody
    • Silencer factor B antibody
    • TCF-5 antibody
    • TCF5 antibody
    • Transcription factor 5 antibody
    see all

Anti-CEBP Beta antibody images

  • All lanes : Anti-CEBP Beta antibody (ab53138) at 1/300 dilution

    Lane 1 : NIH/3T3 cell extract
    Lane 2 : NIH/3T3 cell extract with immunizing peptide


    Predicted band size : 36 kDa
    Observed band size : 36 kDa
  • ab53138 at 1/50 dilution staining CEBP Beta in human lung carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.

References for Anti-CEBP Beta antibody (ab53138)

This product has been referenced in:
  • Mir RA & Chauhan SS Down Regulation of a Matrix Degrading Cysteine Protease Cathepsin L, by Acetaldehyde: Role of C/EBPa. PLoS One 6:e20768 (2011). WB ; Human . Read more (PubMed: 21687683) »
  • Younce CW  et al. MCP-1 (monocyte chemotactic protein-1)-induced protein, a recently identified zinc finger protein, induces adipogenesis in 3T3-L1 pre-adipocytes without peroxisome proliferator-activated receptor gamma. J Biol Chem 284:27620-8 (2009). WB ; Mouse . Read more (PubMed: 19666473) »

See all 2 Publications for this product

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