Overview

  • Product nameAnti-CED6 antibody
    See all CED6 primary antibodies
  • Description
    Rabbit polyclonal to CED6
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 235-265 of Human CED6

  • Positive control
    • CEM cell lysate, Human skeletal muscle tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThis antibody is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab103642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 34 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionMay function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
  • Tissue specificityWidely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
  • Sequence similaritiesBelongs to the ced-6 family.
    Contains 1 PID domain.
  • Cellular localizationCytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes.
  • Information by UniProt
  • Database links
  • Alternative names
    • CED6 antibody
    • Cell death protein 6 homolog antibody
    • Engulfment adapter protein antibody
    • Engulfment adaptor PTB domain containing 1 antibody
    • GULP antibody
    • GULP, engulfment adaptor PTB domain containing 1 antibody
    • GULP1 antibody
    • GULP1_HUMAN antibody
    • Protein GULP antibody
    • PTB domain adapter protein CED 6 antibody
    • PTB domain adapter protein CED-6 antibody
    • PTB domain adaptor protein CED6 antibody
    • PTB domain-containing engulfment adapter protein 1 antibody
    see all

Anti-CED6 antibody images

  • Anti-CED6 antibody (ab103642) at 1/100 dilution + CEM cell lysate at 35 µg

    Predicted band size : 34 kDa
  • IHC analysis in formalin fixed and paraffin embedded Human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining, using ab103642 at a dilution of 1/50.

References for Anti-CED6 antibody (ab103642)

ab103642 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"