Overview

  • Product name
  • Description
    Goat polyclonal to CED6
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    EGTVFCLDPLDSRC

    , corresponding to C terminal amino acids 291-304 of Human CED6

  • Positive control
    • Human kidney tissue; Human Placenta lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab85944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
IHC-P
  • Application notes
    ELISA: 1/64000.
    IHC-P: Use at a concentration of 5 µg/ml.
    WB: Use at a concentration of 0.2 - 0.6 µg/ml for 1hr. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
    • Tissue specificity
      Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
    • Sequence similarities
      Belongs to the ced-6 family.
      Contains 1 PID domain.
    • Cellular localization
      Cytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes.
    • Information by UniProt
    • Database links
    • Alternative names
      • CED6 antibody
      • Cell death protein 6 homolog antibody
      • Engulfment adapter protein antibody
      • Engulfment adaptor PTB domain containing 1 antibody
      • GULP antibody
      • GULP, engulfment adaptor PTB domain containing 1 antibody
      • GULP1 antibody
      • GULP1_HUMAN antibody
      • Protein GULP antibody
      • PTB domain adapter protein CED 6 antibody
      • PTB domain adapter protein CED-6 antibody
      • PTB domain adaptor protein CED6 antibody
      • PTB domain-containing engulfment adapter protein 1 antibody
      see all

    Images

    • ab85944 at 5µg/ml staining CED6 in human kidney by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.
    • Anti-CED6 antibody (ab85944) at 0.2 µg/ml + Human Placenta lysate at 30 µg

      Predicted band size : 35 kDa
      Observed band size : 35 kDa
      Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.

    References

    ab85944 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Our CED6 antibody ab85944 was raised against the synthetic peptide EGTVFCLDPLDSRC, corresponding to C terminal amino acids 291-304 of Human CED6. We recommend the following ELISA protocol:

    http:/...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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