Ceftriaxone disodium salt hemi(heptahydrate) (ab120871)

Overview

  • Product nameCeftriaxone disodium salt hemi(heptahydrate)
  • Description
    β-Lactam antibiotic
  • Biological descriptionPotent β-lactam antibiotic. Effective against Gram-positive and Gram-negative bacteria. Neuroprotective effects in vivo.
  • Purity> 98%

Properties

  • Chemical name(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid disodium salt hemi(heptahydrate)
  • Molecular weight661.59
  • Chemical structureChemical Structure
  • Molecular formulaC18H16N8Na2O7S3.3.5H2O
  • CAS Number104376-79-6
  • PubChem identifier11614223
  • Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
  • Solubility overviewSoluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESO.O.O.O.O.O.O.Nc1scc(n1)\C(=N\OC)C(=O)N[C@@H]3C(=O)N4C(C(=O)O[Na])=C(CSC2=NC(=O)C(O[Na])=NN2C)CS[C@H]34.Nc1scc(n1)\C(=N\OC)C(=O)N[C@@H]3C(=O)N4C(=C(CSC2=NC(=O)C(O[Na])=NN2C)CS[C@H]34)C(=O)O[Na]
  • Source

    Synthetic

  • Research areas

    References for Ceftriaxone disodium salt hemi(heptahydrate) (ab120871)

    This product has been referenced in:
    • Wei J  et al. The beta-lactam antibiotic, ceftriaxone, provides neuroprotective potential via anti-excitotoxicity and anti-inflammation response in a rat model of traumatic brain injury. J Trauma Acute Care Surg 73:654-60 (2012). Read more (PubMed: 22710775) »
    • Gunduz O  et al. Role of GLT-1 transporter activation in prevention of cannabinoid tolerance by the ß-lactam antibiotic, ceftriaxone, in mice. Pharmacol Biochem Behav 99:100-3 (2011). Read more (PubMed: 21536061) »
    • Cleeland R & Squires E Antimicrobial activity of ceftriaxone: a review. Am J Med 77:3-11 (1984). Read more (PubMed: 6093515) »
    • Richards DM  et al. Ceftriaxone. A review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs 27:469-527 (1984). Read more (PubMed: 6329638) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"