Anti-CELF3 antibody - N-terminal (ab171415)

Overview

  • Product name
    Anti-CELF3 antibody - N-terminal
    See all CELF3 primary antibodies
  • Description
    Rabbit polyclonal to CELF3 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: Flow Cyt, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CELF3 aa 2-32 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q5SZQ8

  • Positive control
    • Jurkat and MDA-MB231 cell line lysates; Jurkat cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab171415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/50.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

WB 1/100 - 1/500. Predicted molecular weight: 51 kDa.

Target

  • Function
    RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
  • Tissue specificity
    Expressed in brain.
  • Sequence similarities
    Belongs to the CELF/BRUNOL family.
    Contains 3 RRM (RNA recognition motif) domains.
  • Cellular localization
    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bruno-like protein 1 antibody
    • BRUNOL1 antibody
    • CAG repeat protein 4 antibody
    • CAGH4 antibody
    • CELF-3 antibody
    • CELF3 antibody
    • CELF3_HUMAN antibody
    • CUG-BP- and ETR-3-like factor 3 antibody
    • CUGBP Elav-like family member 3 antibody
    • ELAV-type RNA-binding protein 1 antibody
    • ERDA4 antibody
    • ETR-1 antibody
    • Expanded repeat domain protein CAG/CTG 4 antibody
    • RNA-binding protein BRUNOL-1 antibody
    • TNRC4 antibody
    • Trinucleotide repeat-containing gene 4 protein antibody
    see all

Images

  • All lanes : Anti-CELF3 antibody - N-terminal (ab171415) at 1/100 dilution

    Lane 1 : Jurkat cell line lysate
    Lane 2 : MDA-MB231 cell line lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size: 51 kDa

  • Flow Cytometric analysis of Jurkat cells labeling CELF3 with ab171415 at 1/10 dilution (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

References

ab171415 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab171415.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up