Anti-Cellular Apoptosis Susceptibility antibody (ab52232)


  • Product nameAnti-Cellular Apoptosis Susceptibility antibody
    See all Cellular Apoptosis Susceptibility primary antibodies
  • Description
    Rabbit polyclonal to Cellular Apoptosis Susceptibility
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide (Human)

  • Positive control
    • Extracts from 293 cells.



Our Abpromise guarantee covers the use of ab52232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/40000.
WB 1/500 - 1/1000. Detects a band of approximately 110 kDa (predicted molecular weight: 110 kDa).


  • FunctionExport receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
  • Tissue specificityHighly expressed in proliferating cells.
  • Sequence similaritiesBelongs to the XPO2/CSE1 family.
    Contains 1 importin N-terminal domain.
  • Cellular localizationCytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAS antibody
    • Cellular apoptosis susceptibility protein antibody
    • Chromosome segregation 1 (yeast homolog) like antibody
    • Chromosome segregation 1 Like antibody
    • Chromosome segregation 1 like protein antibody
    • Chromosome segregation 1-like protein antibody
    • Chromosome segregation gene CSE1 antibody
    • CSE 1 antibody
    • CSE 1 chromosome segregation 1 like antibody
    • CSE 1 chromosome segregation 1 like protein antibody
    • CSE 1L antibody
    • CSE1 antibody
    • CSE1 chromosome segregation 1 like (yeast) antibody
    • CSE1 chromosome segregation 1 like antibody
    • CSE1 chromosome segregation 1 like protein antibody
    • CSE1L antibody
    • Exp 2 antibody
    • Exp2 antibody
    • Exportin 2 antibody
    • Exportin-2 antibody
    • Exportin2 antibody
    • Importin alpha re exporter antibody
    • Importin-alpha re-exporter antibody
    • MGC117283 antibody
    • MGC130036 antibody
    • MGC130037 antibody
    • XPO 2 antibody
    • XPO2 antibody
    • XPO2_HUMAN antibody
    see all

Anti-Cellular Apoptosis Susceptibility antibody images

  • All lanes : Anti-Cellular Apoptosis Susceptibility antibody (ab52232) at 1/500 dilution

    Lane 1 : Extracts of 293 cells, untreated.
    Lane 2 : Extracts of 293 cells, treated with the immunising peptide.

    Predicted band size : 110 kDa
    Observed band size : 110 kDa

References for Anti-Cellular Apoptosis Susceptibility antibody (ab52232)

ab52232 has not yet been referenced specifically in any publications.

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