Overview

  • Product nameAnti-Cenexin1/ODF2 antibody
    See all Cenexin1/ODF2 primary antibodies
  • Description
    Rabbit polyclonal to Cenexin1/ODF2
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Guinea pig, Dog, Pig, Chimpanzee, Rhesus monkey, Chinese Hamster, Orangutan, Bat
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 150-200 of Human Cenexin1/ODF2 (NP_702911.1).

  • Positive control
    • HeLa whole cell lysate 293T whole cell lysate
  • General notesShelf Life: 1 year from date of receipt

Properties

Applications

Our Abpromise guarantee covers the use of ab125192 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 95 kDa.
IP Use at 2-10 µg/mg of lysate.

Target

  • FunctionSeems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
  • Tissue specificityTestis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids. Detected in the middle piece and extends to about half the principal piece of the sperm tails.
  • Sequence similaritiesBelongs to the ODF2 family.
  • Post-translational
    modifications
    Tyrosine phosphorylated.
  • Cellular localizationCytoplasm > cytoskeleton > centrosome. Cell projection > cilium. Cytoplasm > cytoskeleton > centrosome > centriole. Cytoplasm > cytoskeleton > spindle pole. Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.
  • Information by UniProt
  • Database links
  • Alternative names
    • 84 kDa outer dense fiber protein antibody
    • Cancer/testis antigen 134 antibody
    • Cenexin 1 antibody
    • Cenexin antibody
    • Cenexin1 variant 1 antibody
    • CT134 antibody
    • FLJ44866 antibody
    • KKT 4 antibody
    • KKT4 antibody
    • MGC111096 antibody
    • MGC9034 antibody
    • ODF 2 antibody
    • ODF 84 antibody
    • odf2 antibody
    • ODF2/1 antibody
    • ODF2/2 antibody
    • ODF84 antibody
    • ODFP2_HUMAN antibody
    • OTTHUMP00000022274 antibody
    • OTTHUMP00000022275 antibody
    • Outer dense fiber of sperm tail 2 antibody
    • Outer dense fiber of sperm tails 2 antibody
    • Outer dense fiber of sperm tails protein 2 antibody
    • Outer dense fiber of sperm tails, 84 kD antibody
    • Outer dense fiber protein 2 antibody
    • Sperm outer dense fiber major protein 2 antibody
    • Sperm tail structural protein antibody
    • Testis specific autoantigen antibody
    see all

Anti-Cenexin1/ODF2 antibody images

  • All lanes : Anti-Cenexin1/ODF2 antibody (ab125192) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : 293T whole cell lysate at 50 µg
    Lane 4 : Jurkat whole cell lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 95 kDa


    Exposure time : 3 minutes
  • Immunoprecipitation : 1 mg of HeLa cell lysate immunoprecipitated with ab125192 at 6 µg/mg lysate; 20% of immunoprecipitate loaded in lane

    Western Blot: Cenexin1/ODF2 antibody (ab125192) at 1 µg/ml

    developed using the ECL technique

    Exposure time : 30 seconds

References for Anti-Cenexin1/ODF2 antibody (ab125192)

ab125192 has not yet been referenced specifically in any publications.

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