Overview

  • Product name
  • Description
    Goat polyclonal to CENTG3
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    NPSAELHRSPSLL

    with a Cysteine residue linker, corresponding to C terminal amino acids 863-875 of Human CENTG3.

  • Positive control
    • Human Kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab115459 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/32000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway.
  • Tissue specificity
    Widely expressed.
  • Sequence similarities
    Belongs to the centaurin gamma-like family.
    Contains 3 ANK repeats.
    Contains 1 Arf-GAP domain.
    Contains 1 PH domain.
  • Cellular localization
    Cytoplasm. In cells upon oxidative stress or in brains of Machado-Joseph disease patients, translocates to PML nuclear bodies.
  • Information by UniProt
  • Database links
  • Alternative names
    • AGAP-3 antibody
    • Agap3 antibody
    • AGAP3_HUMAN antibody
    • ANK repeat and PH domain-containing protein 3 antibody
    • Arf GAP with GTPase, ANK repeat and PH domain containing protein 3 antibody
    • Arf-GAP with GTPase antibody
    • ArfGAP with GTPase domain, ankyrin repeat and PH domain antibody
    • ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 antibody
    • centaurin gamma 3 antibody
    • Centaurin-gamma-3 antibody
    • CENTG3 antibody
    • Cnt-g3 antibody
    • CRAG antibody
    • CRAM-associated GTPase antibody
    • CRMP (collapsin response mediator protein) associated antibody
    • FLJ16146 antibody
    • FLJ34452 antibody
    • MR1-interacting protein antibody
    • MRIP-1 antibody
    • MRIP1 antibody
    • OTTHUMP00000213333 antibody
    • OTTHUMP00000213334 antibody
    • OTTHUMP00000213335 antibody
    • OTTHUMP00000213336 antibody
    • OTTHUMP00000213337 antibody
    see all

Images

  • ab115459 at 5 µg/ml staining CENTG3 in Formalin-fixed, Paraffin-embedded Human kidney tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab115459 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab115459.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up