Overview

  • Product name
  • Description
    Rabbit polyclonal to CEP57
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 86-251 of Human CEP57 (AAH01233).

  • Positive control
    • NT2D1 whole cell lysate; NCI-N87 xenograft; MCF-7 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab104010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.
IHC-P 1/100 - 1/500. Heat mediated antigen retrieval using 10mM Citrate buffer or Tris-EDTA buffer (pH8.0) is recommended.

Target

  • Function
    Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the translokin family.
  • Domain
    The C-terminal region mediates the interaction with microtubules and is able to nucleate and bundles microtubules in vitro.
    The centrosome localization domain (CLD) region mediates the localization to centrosomes and homooligomerization.
  • Cellular localization
    Nucleus. Cytoplasm. Cytoplasm > cytoskeleton > centrosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • Centrosomal protein 57kDa antibody
    • Centrosomal protein of 57 kDa antibody
    • Cep57 antibody
    • Cep57 protein antibody
    • CEP57_HUMAN antibody
    • FGF2 interacting protein antibody
    • FGF2-interacting protein antibody
    • KIAA0092 antibody
    • MVA2 antibody
    • PIG8 antibody
    • Proliferation inducing protein 8 antibody
    • Testis specific protein 57 antibody
    • Testis-specific protein 57 antibody
    • Translokin antibody
    • TSP57 antibody
    see all

Images

  • Anti-CEP57 antibody (ab104010) at 1/3000 dilution + NT2D1 whole cell lysate at 30 µg

    Predicted band size : 57 kDa
  • ab104010, at 1/100 dilution, staining CEP57 in paraffin-embedded NCI-N87 xenograft by Immunohistochemistry.

References

ab104010 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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