The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
FunctionCentrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2.
Sequence similaritiesBelongs to the translokin family.
DomainThe C-terminal region mediates the interaction with microtubules and is able to nucleate and bundles microtubules in vitro. The centrosome localization domain (CLD) region mediates the localization to centrosomes and homooligomerization.