Anti-Ceramide synthase 1 antibody (ab85696)

Overview

  • Product nameAnti-Ceramide synthase 1 antibody
    See all Ceramide synthase 1 primary antibodies
  • Description
    Goat polyclonal to Ceramide synthase 1
  • Specificityab85696 is expected to recognize both reported isoforms (NP_067090.1 and NP_937850.1).
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Synthetic peptide:

    C-KDLREYDTAEAQ

    , corresponding to internal sequence amino acids 318-329 of Human LASS1 (NP_067090.1; NP_937850.1).

  • Positive control
    • Human brain (cerebellum, cerebral cortex and frontal cortex) lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab85696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 40 kDa).

Target

  • FunctionMay be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner.
  • Sequence similaritiesContains 1 TLC (TRAM/LAG1/CLN8) domain.
  • Cellular localizationEndoplasmic reticulum membrane and Endoplasmic reticulum membrane. Golgi apparatus membrane. Isoform 1 may recycle from the Golgi to the endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ceramide synthase 1 antibody
    • CerS1 antibody
    • CERS1_HUMAN antibody
    • LAG1 antibody
    • LAG1 homolog ceramide synthase 1 antibody
    • LAG1 longevity assurance homolog 1 antibody
    • LASS 1 antibody
    • LASS1 antibody
    • Longevity assurance (LAG1 S. cerevisiae) homolog 1 antibody
    • Longevity assurance gene 1 antibody
    • Longevity assurance gene 1 protein homolog 1 antibody
    • MGC90349 antibody
    • Protein LAG1 antibody
    • Protein UOG 1 antibody
    • Protein UOG-1 antibody
    • UOG 1 protein antibody
    • UOG1 antibody
    • Upstream of GDF1 antibody
    see all

Anti-Ceramide synthase 1 antibody images

  • Anti-Ceramide synthase 1 antibody (ab85696) at 1 µg/ml + Human Frontal cortex lysate (in RIPA buffer) at 35 µg

    Predicted band size : 40 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 85 kDa. We are unsure as to the identity of these extra bands.

References for Anti-Ceramide synthase 1 antibody (ab85696)

ab85696 has not yet been referenced specifically in any publications.

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