Anti-Ceramide synthase 2 antibody (ab85567)

Overview

  • Product name
    Anti-Ceramide synthase 2 antibody
    See all Ceramide synthase 2 primary antibodies
  • Description
    Rabbit polyclonal to Ceramide synthase 2
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 72-121 (EKTRLRAPPN ATLEHFYLTS GKQPKQVEVE LLSRQSGLSG RQVERWFRRR) of Human LASS2 (NP_071358).

  • Positive control
    • Human fetal brain lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis.
  • Tissue specificity
    Expressed in kidney, liver, brain, heart, placenta and lung.
  • Sequence similarities
    Contains 1 homeobox DNA-binding domain.
    Contains 1 TLC (TRAM/LAG1/CLN8) domain.
  • Cellular localization
    Nucleus membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ceramide synthase 2 antibody
    • CerS 2 antibody
    • CerS2 antibody
    • CERS2_HUMAN antibody
    • FLJ10243 antibody
    • L3 antibody
    • LAG1 homolog ceramide synthase 2 antibody
    • LAG1 longevity assurance 2 antibody
    • LAG1 longevity assurance homolog 2 antibody
    • LASS 2 antibody
    • Longevity assurance (LAG1 S. cerevisiae) homolog 2 antibody
    • MGC987 antibody
    • SP 260 antibody
    • SP260 antibody
    • TMSG 1 antibody
    • TMSG1 antibody
    • Tumor metastasis suppressor antibody
    • Tumor metastasis suppressor gene 1 protein antibody
    • Tumor metastasis-suppressor gene 1 protein antibody
    see all

Images

  • Anti-Ceramide synthase 2 antibody (ab85567) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal brain lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 45 kDa
    Observed band size : 45 kDa
    Additional bands at : 30 kDa,35 kDa. We are unsure as to the identity of these extra bands.Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling LASS2 with ab85567 at 5.0µg/ml.

References

ab85567 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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