Overview

  • Product nameAnti-CES2 antibody
    See all CES2 primary antibodies
  • Description
    Rabbit polyclonal to CES2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 343-373 of Human CES2 (NP_003860).

  • Positive control
    • Human hepatocarcinoma tissue; MCF7 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab111751 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 62 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionInvolved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methyumbelliferyl acetate, heroin and 6-monoacetylmorphine.
  • Tissue specificityPreferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.
  • Sequence similaritiesBelongs to the type-B carboxylesterase/lipase family.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localizationEndoplasmic reticulum lumen.
  • Information by UniProt
  • Database links
  • Alternative names
    • Carboxylesterase 2 (intestine, liver) antibody
    • Carboxylesterase 2 antibody
    • CE-2 antibody
    • CES2 antibody
    • CES2A1 antibody
    • Cocaine esterase antibody
    • EC 3.1.1.1 antibody
    • EST2_HUMAN antibody
    • hCE-2 antibody
    • ICE antibody
    • Iintestinal carboxylesterase liver carboxylesterase 2 antibody
    • Intestinal carboxylesterase; liver carboxylesterase-2 antibody
    • Methylumbelliferyl acetate deacetylase 2 antibody
    • PCE 2 antibody
    • PCE-2 antibody
    see all

Anti-CES2 antibody images

  • Anti-CES2 antibody (ab111751) at 1/100 dilution + MCF7 cell lysates at 35 µg

    Predicted band size : 62 kDa
  • Immunohistochemistry analysis of CES2 expression in formalin fixed and paraffin embedded Human hepatocarcinoma tissue using 1/50 ab111751 followed by a peroxidase conjugated secondary antibody and DAB staining.

References for Anti-CES2 antibody (ab111751)

ab111751 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for your interest in ab111751.

The immunogen sequence for this product is from aa 343 to aa 373 of the Human CES2: NNEFGWLI PKVMRIYDTQ KEMDREASQA ALQ.

To our knowledge, ab111751 has only been tested in Human. The...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"