The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100. Predicted molecular weight: 55 kDa.
FunctionInvolved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol.
Tissue specificityExpressed by the liver and secreted in plasma.
Involvement in diseaseDefects in CETP are a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL). Defects in CETP are the cause of cholesteryl ester transfer protein deficiency (CETP deficiency) [MIM:607322]. This is an autosomal dominant condition associated with increased HDL cholesterol levels.
Sequence similaritiesBelongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.