Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Sequence
      CDSGRVRTDAPD
    • Amino acids
      140 to 151

Specifications

Our Abpromise guarantee covers the use of ab41789 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    competitive binding assays

    Neutralising

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • BPIFF
    • CETP
    • CETP_HUMAN
    • Cholesteryl ester transfer protein
    • Cholesteryl ester transfer protein plasma
    • HDLCQ10
    • Lipid transfer protein I
    see all
  • Function
    Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol.
  • Tissue specificity
    Expressed by the liver and secreted in plasma.
  • Involvement in disease
    Defects in CETP are a cause of hyperalphalipoproteinemia (HYPALIP) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL).
    Defects in CETP are the cause of cholesteryl ester transfer protein deficiency (CETP deficiency) [MIM:607322]. This is an autosomal dominant condition associated with increased HDL cholesterol levels.
  • Sequence similarities
    Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
  • Cellular localization
    Secreted > extracellular space.
  • Information by UniProt

References

ab41789 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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