Overview

  • Product nameAnti-Cezanne antibody
    See all Cezanne primary antibodies
  • Description
    Mouse monoclonal to Cezanne
  • Tested applicationsSuitable for: WB, ELISA, IHC-P, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment of Human Cezanne (amino acids 759-859) with proprietary tag, 11kDa. (NP_064590.2).

  • Positive control
    • Human endometrium tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab118387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 93 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 3 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Sandwich ELISA Use at an assay dependent concentration.

Target

  • FunctionHas deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.
  • Tissue specificityWidely expressed. Abundant in kidney, heart and fetal liver. Expressed differentially among B-cells at distinct developmental stages. Higher expression seen in primary immature B-cells as compared to the mature cells.
  • Sequence similaritiesBelongs to the peptidase C64 family.
    Contains 1 A20-type zinc finger.
    Contains 1 OTU domain.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cellular zinc finger anti NF kappa B protein antibody
    • Cellular zinc finger anti-NF-kappa-B protein antibody
    • CEZANNE antibody
    • HGNC:16683 antibody
    • OTU domain containing protein 7B antibody
    • OTU domain-containing protein 7B antibody
    • OTU7B_HUMAN antibody
    • OTUD7B antibody
    • ZA20D1 antibody
    • Zinc finger A20 domain containing protein 1 antibody
    • Zinc finger A20 domain-containing protein 1 antibody
    • Zinc finger protein Cezanne antibody
    see all

Anti-Cezanne antibody images

  • Anti-Cezanne antibody (ab118387) at 5 µg/ml + Recombinant immunogen at 0.2 µg

    Predicted band size : 93 kDa
  • ab118387, at 3 ug/ml, staining Cezanne in formalin-fixed, paraffin-embedded Human endometrium tissue by Immunohistochemistry.
  • Detection limit for ab118387 is 0.3 ng/ml as a capture antibody.

References for Anti-Cezanne antibody (ab118387)

ab118387 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"