Overview

  • Product name
    Anti-Cezanne antibody
  • Description
    Rabbit polyclonal to Cezanne
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 756-784 of Human Cezanne (NP_064590.2).

  • Positive control
    • MDA-MB453 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab123309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 93 kDa.

Target

  • Function
    Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.
  • Tissue specificity
    Widely expressed. Abundant in kidney, heart and fetal liver. Expressed differentially among B-cells at distinct developmental stages. Higher expression seen in primary immature B-cells as compared to the mature cells.
  • Sequence similarities
    Belongs to the peptidase C64 family.
    Contains 1 A20-type zinc finger.
    Contains 1 OTU domain.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cellular zinc finger anti NF kappa B protein antibody
    • Cellular zinc finger anti-NF-kappa-B protein antibody
    • CEZANNE antibody
    • HGNC:16683 antibody
    • OTU domain containing protein 7B antibody
    • OTU domain-containing protein 7B antibody
    • OTU7B_HUMAN antibody
    • OTUD7B antibody
    • ZA20D1 antibody
    • Zinc finger A20 domain containing protein 1 antibody
    • Zinc finger A20 domain-containing protein 1 antibody
    • Zinc finger protein Cezanne antibody
    see all

Images

  • Anti-Cezanne antibody (ab123309) at 1/100 dilution + MDA-MB453 cell line lysates at 35 µg

    Predicted band size : 93 kDa

References

This product has been referenced in:
  • Guo F  et al. miR-218 regulates focal adhesion kinase-dependent TGFß signaling in fibroblasts. Mol Biol Cell 25:1151-8 (2014). WB ; Human . Read more (PubMed: 24501422) »

See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab123309.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up