Overview

  • Product name
  • Description
    Goat polyclonal to CHCHD3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Cow
  • Immunogen

    Synthetic peptide corresponding to internal amino acids 151-164 (

    RSSEFYRVTTEQYQ

    ) of Human CHCHD3 (NP_060282.1).

  • Positive control
    • Human placenta lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab99491 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 26 kDa.

Target

  • Function
    Required for maintenance of mitochondrial crista integrity and mitochondrial function. May act as a scaffolding protein that stabilizes protein complexes involved in crista architecture and protein import. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.
  • Tissue specificity
    Detected at low levels in brain, placenta, lung, liver, kidney and pancreas with increased levels in heart and skeletal muscle. Higher expression in primary lung cancers than in normal lung tissue.
  • Sequence similarities
    Contains 1 CHCH domain.
  • Cellular localization
    Mitochondrion inner membrane. Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CHCH3_HUMAN antibody
    • CHCHD 3 antibody
    • Chchd3 antibody
    • Coiled coil helix coiled coil helix domain containing 3 antibody
    • Coiled coil helix coiled coil helix domain containing protein 3 mitochondrial antibody
    • Coiled-coil-helix-coiled-coil-helix domain-containing protein 3 antibody
    • FLJ20420 antibody
    • MINOS3 antibody
    • mitochondrial antibody
    • Mitochondrial inner membrane organizing system 3 antibody
    • PPP1R22 antibody
    • Protein phosphatase 1 regulatory subunit 22 antibody
    see all

Images

  • Anti-CHCHD3 antibody (ab99491) at 0.3 µg/ml + Human Placenta lysate (in RIPA buffer) at 35 µg

    Predicted band size : 26 kDa

References

ab99491 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab99491.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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