Overview

  • Product nameAnti-CHIC2 antibody
  • Description
    Rabbit polyclonal to CHIC2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 19-68 (EEQLLKYSPD PVVVRGSGHV TVFGLSNKFE SEFPSSLTGK VAPEEFKASI) of Human CHIC2 (NP_036242).

  • Positive control
    • HepG2 cell lysate; Human intestine tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG

Associated products

Applications

Our Abpromise guarantee covers the use of ab105536 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.25 µg/ml. Predicted molecular weight: 19 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

Target

  • Involvement in diseaseNote=A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6.
  • Sequence similaritiesBelongs to the CHIC family.
  • Post-translational
    modifications
    Palmitoylation in the CHIC motif is required for membrane association.
  • Cellular localizationCell membrane. Cytoplasmic vesicle. Also present at a Golgi-like vesicular compartment and at scattered vesicles.
  • Information by UniProt
  • Database links
  • Alternative names
    • BrX-like translocated in leukemia antibody
    • BTL antibody
    • Chic2 antibody
    • CHIC2_HUMAN antibody
    • Cystein-rich hydrophobic domain 2 antibody
    • Cysteine-rich hydrophobic domain 2 protein antibody
    • MGC21173 antibody
    see all

Anti-CHIC2 antibody images

  • Anti-CHIC2 antibody (ab105536) at 0.25 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 19 kDa
  • ab105536, at 8 µg/ml, staining CHIC2 in paraffin embeded Human intestine tissue by Immunohistochemistry. The arrows indicate cells with positive label: epithelial cells of intestinal villus. Magnification: 400X

References for Anti-CHIC2 antibody (ab105536)

ab105536 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"