Anti-CHIPS antibody [JNC1] (ab37241)
Key features and details
- Mouse monoclonal [JNC1] to CHIPS
- Suitable for: Flow Cyt, IHC-Fr, WB, IHC-P
- Reacts with: Staphylococcus aureus
- Isotype: IgG1
Overview
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Product name
Anti-CHIPS antibody [JNC1] -
Description
Mouse monoclonal [JNC1] to CHIPS -
Host species
Mouse -
Specificity
ab37241 reacts with N-terminus of CHIPS.
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Tested applications
Suitable for: Flow Cyt, IHC-Fr, WB, IHC-Pmore details -
Species reactivity
Reacts with: Staphylococcus aureus -
Immunogen
Full length native protein (purified) corresponding to CHIPS.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 0.1% BSA, PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
JNC1 -
Isotype
IgG1 -
Research areas
Associated products
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ChIP Related Products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab37241 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
1/10.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
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IHC-Fr |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 17 kDa.
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IHC-P |
Use at an assay dependent concentration.
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Notes |
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Flow Cyt
1/10. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
IHC-Fr
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 17 kDa. |
IHC-P
Use at an assay dependent concentration. |
Target
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Relevance
The bacterial pathogen Staphylococcus aureus is insensitive to antimicriobial host defense peptides like defensins, protegrins, platelet microbicidial proteins and bacteriocins. Staphylococci have developed various resistance mechanisms including those specific for bacteriocins and several host defence peptides. A protein belonging to the resistance mechanism of Staphylococcus aureus is known as CHIPS ( Chemotaxis Inhibiting Protein for Staphylococcus aureus). CHIPS is a proteins that inhibits chemotaxis of neutrophils by blocking the Formyl Peptide Receptor (FPR) and C5a Receptor on neutrophils. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 2861356 Staphylococcus aureus
- SwissProt: Q6GFB3 Staphylococcus aureus
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Alternative names
- Chemotaxis inhibiting protein antibody
- Chemotaxis inhibitory protein antibody
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab37241 has been referenced in 1 publication.
- Quiblier C et al. Secretome analysis defines the major role of SecDF in Staphylococcus aureus virulence. PLoS One 8:e63513 (2013). WB . PubMed: 23658837