Overview

  • Product name
    Anti-CHIPS antibody [JNC1]
  • Description
    Mouse monoclonal [JNC1] to CHIPS
  • Specificity
    ab37241 reacts with N-terminus of CHIPS
  • Tested applications
    Suitable for: Flow Cyt, IHC-Fr, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Staphylococcus aureus
  • Immunogen

    Full length native protein (purified)

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.01% Sodium Azide
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    JNC1
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab37241 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
IHC-Fr
WB
IHC-P
  • Application notes
    Flow Cyt: Use at an assay dependent dilution. Starting dilution 1/10.
    IHC-Fr: Use at an assay dependent dilution.
    IHC-P: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Starting dilution 1/100. Predicted molecular weight: 17 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      The bacterial pathogen Staphylococcus aureus is insensitive to antimicriobial host defense peptides like defensins, protegrins, platelet microbicidial proteins and bacteriocins. Staphylococci have developed various resistance mechanisms including those specific for bacteriocins and several host defence peptides. A protein belonging to the resistance mechanism of Staphylococcus aureus is known as CHIPS ( Chemotaxis Inhibiting Protein for Staphylococcus aureus). CHIPS is a proteins that inhibits chemotaxis of neutrophils by blocking the Formyl Peptide Receptor (FPR) and C5a Receptor on neutrophils.
    • Cellular localization
      Secreted
    • Database links
      • Alternative names
        • Chemotaxis inhibiting protein antibody
        • Chemotaxis inhibitory protein antibody

      References

      This product has been referenced in:
      • Quiblier C  et al. Secretome analysis defines the major role of SecDF in Staphylococcus aureus virulence. PLoS One 8:e63513 (2013). WB . Read more (PubMed: 23658837) »

      See 1 Publication for this product

      Customer reviews and Q&As

      There are currently no Customer reviews or Questions for ab37241.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

      Sign up