Overview

  • Product nameAnti-CHL1 antibody
    See all CHL1 primary antibodies
  • Description
    Rabbit polyclonal to CHL1
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to amino acids 788-1025 of Human CHL1, accession number NM_006614.

  • Positive control
    • HL60 and Jurkat cell lysates.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab106269 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 135 kDa (predicted molecular weight: 137 kDa).
IHC-P Use at an assay dependent concentration.

Target

  • RelevanceCHL1 is an extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. CHL1 plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. CHL1 may play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins and recruits ANK3 to the plasma membrane.
  • Cellular localizationCell Membrane and Secreted
  • Database links
  • Alternative names
    • CALL antibody
    • Cell adhesion molecule with homology to L1CAM (close homolog of L1) antibody
    • Cell adhesion molecule with homology to L1CAM (close homologue of L1) antibody
    • Cell adhesion molecule with homology to L1CAM antibody
    • Close homolog of L1 antibody
    • FLJ44930 antibody
    • L1 cell adhesion molecule 2 antibody
    • L1CAM2 antibody
    • MGC132578 antibody
    • Neural cell adhesion molecule antibody
    see all

Anti-CHL1 antibody images

  • All lanes : Anti-CHL1 antibody (ab106269) at 1/1000 dilution

    Lane 1 : HL60 cell lysate
    Lane 2 : Jurkat cell lysate


    Predicted band size : 137 kDa

References for Anti-CHL1 antibody (ab106269)

ab106269 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106269.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"