Anti-Chlamydia trachomatis LPS antibody [CL21-335.2.3.] (ab41196)

Overview

  • Product nameAnti-Chlamydia trachomatis LPS antibody [CL21-335.2.3.]
    See all Chlamydia trachomatis LPS primary antibodies
  • Description
    Mouse monoclonal [CL21-335.2.3.] to Chlamydia trachomatis LPS
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Chlamydia trachomatis
  • Immunogen

    Tissue/ cell preparation: Chlamydia trachomatis LPS elementary bodies.

Properties

Applications

Our Abpromise guarantee covers the use of ab41196 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/102400.

Target

  • RelevanceLPS is a major component of the cell membrane of Gram negative bacteria, contributing greatly to the structural integrity of the bacteria, and protecting the membrane from certain kinds of chemical attack. LPS is an endotoxin, inducing a strong response from normal animal immune systems. LPS function has been under experimental research for several years due to its role in activating many transcriptional factors, which become active after stimulation with LPS. LPS also induces many types of mediators involved in septic shock. Chlamydia trachomatis is an intracellular organism. It has a genome size of approximately 500-1000kB and contains both RNA and DNA. Colonization of Chlamydia begins with attachment to sialic acid receptors on the eye, throat or genitalia. It persists at body sites that are inaccessible to phagocytes, T-cells, and B-cells. It also exists as 15 different serotypes. These serotypes cause four major diseases in humans: endemic trachoma (caused by serotypes A and C), sexually transmitted disease and inclusion conjunctivitis (caused by serotypes D and K), and lymphogranuloma venereum (caused by serotypes L1, L2, and L3). Studies reveal that Chlamydia, because of its cell wall, is able to inhibit phagolysosome fusion in phagocytes. The cell wall is proposed to be gram-negative in that it contains an outer lipopolysaccharide (LPS) membrane, but it lacks peptidoglycan in its cell wall.
  • Alternative names
    • C.trachomatis antibody

References for Anti-Chlamydia trachomatis LPS antibody [CL21-335.2.3.] (ab41196)

ab41196 has not yet been referenced specifically in any publications.

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