• Product nameAnti-CHMP5 antibody
    See all CHMP5 primary antibodies
  • Description
    Rabbit polyclonal to CHMP5
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow, Zebrafish
  • Immunogen

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 172 of Human CHMP5

  • Positive control
    • 293T, A431, H1299, HeLa S3, HepG2 whole cell lysates (WB). NCIN87 xenograft (IHC).


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab96273 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 25 kDa.
IHC-P 1/100 - 1/500.


  • FunctionProbable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.
  • Sequence similaritiesBelongs to the SNF7 family.
  • Cellular localizationCytoplasm > cytosol. Endosome membrane. Localizes to the midbody of dividing cells. Localized in two distinct rings on either side of the Fleming body.
  • Information by UniProt
  • Database links
  • Alternative names
    • apoptosis-related protein PNAS-2 antibody
    • C9orf83 antibody
    • CGI 34 antibody
    • Charged multivesicular body protein 5 antibody
    • CHMP 5 antibody
    • CHMP family, member 5 antibody
    • chmp5 antibody
    • CHMP5_HUMAN antibody
    • Chromatin modifying protein 5 antibody
    • Chromatin-modifying protein 5 antibody
    • Chromosome 9 open reading frame 83 antibody
    • HGNC:26942 antibody
    • HSPC177 antibody
    • hVps60 antibody
    • PNAS 2 antibody
    • SNF7 domain containing protein 2 antibody
    • SNF7 domain-containing protein 2 antibody
    • SNF7DC2 antibody
    • Vacuolar protein sorting 60 antibody
    • Vacuolar protein sorting-associated protein 60 antibody
    • Vps60 antibody
    see all

Anti-CHMP5 antibody images

  • All lanes : Anti-CHMP5 antibody (ab96273) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : H1299 whole cell lysate
    Lane 4 : HeLa S3 whole cell lysate
    Lane 5 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 25 kDa
  • Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using ab96273 at 1/100 dilution

References for Anti-CHMP5 antibody (ab96273)

ab96273 has not yet been referenced specifically in any publications.

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